Dr. Vladimir Gavrilov
Born: 1950, Tajikistan
Academic Qualifications:
    Ph.D. , 1988, Institute of Obstetrics and Gynecology. the USSR Academy of Medical Sciences. Leningrad,
Academic Positions:
Department of Clinical Biochemistry and Pharmacology - Research Grade C

Research Interests:
Prostate Cancer treatment usimg a) combination of histone deacetylase inhibitors with the active metabolite of vitamin D, 1,25(OH)2D3 and with non-steroidal anti-inflammatory drugs, b) combination of histone deacetylase inhibitors with irradiation and radiomimetic anticancer drugs
Research Projects:
INTRACELLULAR SIGNALING PATHWAYS RESPONSIBLE FOR THE SENSITIZATION TO IONIZING RADIATION OF PROSTATE CANCER CELLS PRETREATED WITH A COMBINATION OF 1,25(OH)2D3 AND SODIUM VALPROATE
Publications:
  • Gavrilov V, Harman-Boehm I, Amichay D, Tessler G, Shuster T, Friger M,Gorodischer R . Kidney function and retinol status in type 2 diabetes mellitus patients Acta Diabetol 49: 137-143 (2012)
  • Gavrilov V, Leibovich Y, Ariad S, Lavrenkov K, Shany S. A combined pretreatment of 1,25-dihydroxyvitamin D3 and sodium valproate enhances the damaging effect of ionizing radiation on prostate cancer cells J Steroid Biochem Mol Biol 121: 391-394 (2010)
  • Belochitski O, Ariad S, Shany S, Fridman V, Gavrilov V. . Efficient dual treatment of the hormone-refractory prostate cancer cell line DU145 with cetuximab and 1,25-dihydroxyvitamin D3 In Vivo 21: 371-376 (2007)
  • Gavrilov V, Yermiahu T, Gorodischer R. . Renal pathology and retinol status in multiple myeloma patients Kidney Int 69: 173-177 (2006)
  • Gavrilov V, Steiner M, Shany S. . The combined treatment of 1,25-dihydroxyvitamin D3 and a non-steroid anti-inflammatory drug is highly effective in suppressing prostate cancer cell line (LNCaP) growth. Anticancer Res 25: 3425-3429 (2005)
  • Gavrilov V, Weksler N, Ahmed A, Gorodischer R.. Urinary excretion of vitamin A in critically ill patients complicated with acute renal failure Ren Fail 26: 589-590 (2004)
  • Sintov AC, Krymberk I, Gavrilov V, Gorodischer R. . Transdermal delivery of paracetamol for paediatric use: effects of vehicle formulations on the percutaneous penetration J Pharm Pharmacol 55: 911-919 (2003)
  • Gavrilov V, Berkovitch M, Ling G, Brenner-Zadda G, Lifshitz M, Gorodischer R. . Unapproved prescriptions in two pediatric intensive care units in Israel Curr Ther Res Clin Exp 64: 734-42 (2003)
  • Gavrilov V, Yermiahu T, Gorodischer R. . Urinary excretion of retinol in patients with multiple myeloma: a preliminary study Amer J Hematol 74: 202-204 (2003)
  • Asa I, Ivashkova Y, Artru AA, Lifshitz M, Gavrilov V, Azab AN, Kapuler V, Alouchin A, Rachinsky M, Pruneau D, Shapira Y, Kaplanski J. . LF 16-0687 Ms,a new bradykinin B2 receptor antagonist, improves neurologic outcome but not brain tissue prostaglandin E2 release in a rat model of closed head trauma combined with ethanol intoxication J Trauma 54: 881-887 (2003)
  • Lifshitz M, Gavrilov V. . Adverse reactions to metoclopramide in young children:a 6-year retrospective study and review of the literature Pharm Technol 18: 125-127 (2002)
  • Lifshitz M, Gavrilov V. . Acute lindane poisoning in a child Isr Med Assoc J 4: 731-732 (2002)
  • Lifshitz M, Gavrilov V. . Deliberate self-poisoning in adolescents Isr Med Assoc J 4: 283-284 (2002)
  • Lifshitz M, Gavrilov V, Grossman Z, Binsthok M, Hornik D, Rozemblum H,Chemni S, Alkrinawi S, Miron D, Gorodischer R. . Unapproved prescription practices in primary pediatric clinics in Israel: a prospective analysis Curr Ther Res Clin Exp 63: 830-837 (2002)
  • Lifshitz M, Gavrilov V. . Acute valproic acid poisoning in young children Pharm Technol 17: 151- 153 (2001)
  • Lifshitz M, Gavrilov V, Galil A, Landau D. . A four year survey of neonatal narcotic withdrawal: evaluation and treatment Isr Med Assoc J 3: 17-20 (2001)
  • Lifshitz M, Gavrilov V, Gorodischer R. . Off-label and unlicensed use of antidotes in paediatric patients. Eur J Clin Fharmacol 56: 839-841 (2001)
  • Lifshitz M, Gavrilov V. . Central nervous system toxicity and early peripheral neuropathy following dermal exposure to methyl bromide J Toxicol Clin Toxicol 38: 799-801 (2000)
  • Lifshitz M, Gavrilov V. . Acute poisoning in children Isr Med Assoc J 2: 504-506 (2000)
  • Gavrilov V, Lifshitz M, Levy J, Gorodischer R. . Unlicensed and off-label medication use in a general pediatrics ambulatory hospital unit in Israel Isr Med Assoc J 2: 595-597 (2000)
  • Lifshitz M, Gavrilov V, Sofer S. . Signs and symptoms of carbamazepine overdose in young children Pediat Emerg Care 16: 26-27 (2000)
  • Lifshitz M, Gavrilov V, Lifshitz T. . Methanol intoxication victims are suitable donors for corneal transplantation Cell Tissue Bank 1: 129-131 (2000)
  • Gavrilov V, Lifshitz T, Shany S, Weinstein O, Lifshitz M. . Tear/plasma urea ratio as a correction coefficient for drug monitoring in tears. Pharm Technol 16: 18-20 (2000)
  • Lifshitz M, Gavrilov V, Gorodischer R. . Unlicensed and off-label drug use in hospitalized children. Harefuah 137: 532-534 (1999)
  • Khamaisi M, Rudich A, Beeri I, Pessler D, Friger M, Gavrilov V, Tritschler H, Bashan N. . Metabolic effects of γ-linolenic acid-α-lipoic acid conjugate in streptozotocin diabetic rats. Antioxid Redox Signal 1: 523-534 (1999)
  • Lifshitz M, Weinstein O, Gavrilov V, Rosenthal G, Lifshitz T. . Acetaminophen (paracetamol) levels in human tears. Ther Drug Monit 21: 544-546 (1999)
  • Gavrilov V, Levine J, Agam G, Belmaker RH. . Lithium enhancement of the prolactin response to 5-hydroxytryptophan is not reversible by inositol. Prog Neuro-Psychopharmacol & Biol Psychiat 22: 223-228 (1998)
Book Chapters:
  • Gavrilov V, Gorodischer R, Renal handling of retinol in kidney disease, Vitamin A: New Research, I.T. Loessing , 125 – 137, Nova Science Publisher, Inc. New York , 2007
Keywords:
Phones:
  1. Phone: 972-8-6244525
Email:gavrilov@bgu.ac.il
vladimirga@clalit.org.il